Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SNCA | P37840 | 2/20 | 0.46 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.46 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.46 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11847929 | 0.88 | TSHR (0.60) | TSHRUTS2RLMNATP53APP | |
| SCHEMBL11851828 | 0.82 | TSHR (0.72) | TSHRHTTSOS1KMT2AMEN1 | |
| SCHEMBL11850062 | 0.82 | TSHR (0.86) | TSHRHTTSOS1KMT2AMEN1 | |
| SCHEMBL11843146 | 0.81 | SOS1 (0.74) | TSHRHTTSOS1KMT2AMEN1 | |
| SCHEMBL11876237 | 0.80 | MAPT (0.45) | TSHRUTS2RKMT2ALMNATP53 | |
| SCHEMBL11850946 | 0.79 | TSHR (0.70) | TSHRHTTSOS1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11851095 | 0.79 | TSHR (0.73) | TSHRHTTKMT2AMEN1TP53 | |
| SCHEMBL11800639 | 0.79 | RXFP1 (0.48) | TSHRUTS2RKMT2AMEN1TP53 | |
| SCHEMBL11845463 | 0.77 | TSHR (0.57) | TSHRUTS2RHTTSOS1KMT2A | |
| SCHEMBL11855278 | 0.75 | TSHR (0.75) | TSHRHTTSOS1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3969506-A | BRONCHODILATOR | SANDOZ, INC. (US) | 1976-07-13 | — | — | US | disclosed |