SCHEMBL11845552

SCHEMBL11845552

Cc1ccc(C(N)=O)cc1CP(=O)(O)O

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 3/20 0.55
PGK2 P07205 3/20 0.55
PARP1 P09874 1/20 0.41
SLC6A2 P23975 2/20 0.39
SLC6A4 P31645 2/20 0.39
SLC6A3 Q01959 2/20 0.39
KCNH2 Q12809 1/20 0.39
F11 P03951 1/20 0.39
MAPK14 Q16539 2/20 0.38
MAPT P10636 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11419017 0.80 PARP1 (0.47) PARP1SLC6A2SLC6A4SLC6A3KCNH2
SCHEMBL30006284 0.77 PARP1 (0.44) PARP1SLC6A2SLC6A4SLC6A3KCNH2
SCHEMBL6175216 0.76 SLC6A2 (0.57) PARP1SLC6A2SLC6A4SLC6A3KCNH2
SCHEMBL28752739 0.75 PARP1 (0.42) PARP1SLC6A2SLC6A4SLC6A3KCNH2
SCHEMBL14919614 0.74 PGK1 (0.60) PGK1PGK2TDP1
SCHEMBL9170269 0.73 PGK1 (0.86) PGK1PGK2
SCHEMBL13636371 0.73 HPGD (0.43) PARP1SLC6A2SLC6A4SLC6A3KCNH2
SCHEMBL1002832 0.72 PRSS1 (0.61) PARP1MAPTTDP1MAPK1
SCHEMBL29503140 0.72 PRSS1 (0.61) PARP1MAPTTDP1MAPK1
SCHEMBL11845540 0.70 PGK1 (0.46) PGK1PGK2PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3935162-A Dialkyl aromatic amidomethyl phosphonate flame retardants HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1976-01-27 US disclosed