Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11834426 | 0.85 | HPGD (0.46) | PTGS2ALDH1A1AKR1C3AKR1C2MEN1 | |
| SCHEMBL11851792 | 0.85 | PTGS2 (0.42) | PPARGPPARAPTGS2ALDH1A1PKM | |
| SCHEMBL11842923 | 0.84 | PTGS1 (0.47) | PPARGPPARAPTGS2ALDH1A1AKR1C3 | |
| SCHEMBL11833272 | 0.84 | ALDH1A1 (0.44) | PTGS2CA1CA2CA9ALDH1A1 | |
| SCHEMBL11845939 | 0.84 | ALDH1A1 (0.44) | PTGS2ALDH1A1PKMAKR1C3AKR1C2 | |
| SCHEMBL11847804 | 0.84 | PTGS2 (0.41) | PPARGPPARAPTGS2ALDH1A1PKM | |
| SCHEMBL11844932 | 0.84 | LTB4R2 (0.46) | PTGS2CA12CA1CA2CA9 | |
| SCHEMBL11840116 | 0.84 | CYP2A6 (0.44) | PTGS2MMEDPP4DPP7AKR1C3 | |
| SCHEMBL11846658 | 0.83 | CA12 (0.43) | PPARGPPARAPTGS2CA12CA1 | |
| SCHEMBL11837769 | 0.83 | PTGS2 (0.41) | PTGS2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3941821-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETICS | WILLIAM H. RORER, INC. (US) | 1976-03-02 | — | — | US | disclosed |