Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.76 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11836498 | 1.00 | PTGS2 (0.76) | PTGS2PTGS1 | |
| SCHEMBL11845946 | 1.00 | PTGS2 (0.76) | PTGS2PTGS1 | |
| SCHEMBL5112013 | 0.89 | PTGS2 (0.84) | PTGS2PTGS1 | |
| Sermetacin SCHEMBL11850010 | 0.87 | PTGS2 (0.81) | PTGS2PTGS1 | |
| Sermetacin SCHEMBL42767 | 0.87 | PTGS2 (0.81) | PTGS2PTGS1 | |
| Sermetacin SCHEMBL11844892 | 0.87 | PTGS2 (0.81) | PTGS2PTGS1 | |
| SCHEMBL11849998 | 0.86 | PTGS2 (0.82) | PTGS2PTGS1 | |
| SCHEMBL11844648 | 0.86 | PTGS2 (0.82) | PTGS2PTGS1 | |
| SCHEMBL14405006 | 0.85 | PTGS2 (1.00) | PTGS2PTGS1 | |
| Oxametacin SCHEMBL29378857 | 0.85 | PTGS1 (1.00) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962471-A | Indolylacetylamino acid derivatives, process for their preparation, and pharmaceutical compositions | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-06-08 | — | — | US | claimed |