Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | IL1RN | P18510 | 2/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | YARS1 | P54577 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11859692 | 0.92 | ERAP2 (0.49) | CTSKIL1RNERAP2ERAP1LCK | |
| SCHEMBL11855613 | 0.90 | LCK (0.52) | ERAP2ERAP1KDM4EUSP2EGFR | |
| SCHEMBL11861185 | 0.89 | YARS1 (0.53) | ERAP2ERAP1KDM4EUSP2EGFR | |
| SCHEMBL11857396 | 0.89 | YARS1 (0.53) | ERAP2ERAP1KDM4EUSP2EGFR | |
| SCHEMBL20881521 | 0.89 | LTA4H (0.57) | CTSKLTA4H | |
| SCHEMBL22475577 | 0.89 | LTA4H (0.57) | CTSKLTA4H | |
| SCHEMBL11680813 | 0.89 | LTA4H (0.57) | CTSKLTA4H | |
| SCHEMBL11683261 | 0.89 | LTA4H (0.57) | CTSKLTA4H | |
| SCHEMBL11682299 | 0.89 | LTA4H (0.57) | CTSKLTA4H | |
| Hydrochloric Acid SCHEMBL11681832 | 0.88 | LTA4H (0.56) | CTSKLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3939253-A | Novel, transient pro-drug forms of l-dopa useful in the treatment of parkinson's disease | INTERX RESEARCH CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |