Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 5/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 5/20 | 0.49 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.49 |
| ▸ | IL1RN | P18510 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11847439 | 0.92 | CTSK (0.48) | ERAP2ERAP1IL1RNCTSKLCK | |
| SCHEMBL11855613 | 0.90 | LCK (0.52) | ERAP2ERAP1LNPEPPOLBTACR1 | |
| SCHEMBL11857396 | 0.89 | YARS1 (0.53) | ERAP2ERAP1LNPEPPOLBTACR1 | |
| SCHEMBL11861185 | 0.89 | YARS1 (0.53) | ERAP2ERAP1LNPEPPOLBTACR1 | |
| SCHEMBL16984879 | 0.89 | CTSB (0.55) | ERAP2ERAP1IL1RNPOLBCTSK | |
| SCHEMBL21244283 | 0.89 | CTSB (0.55) | ERAP2ERAP1IL1RNPOLBCTSK | |
| SCHEMBL18257521 | 0.89 | CTSB (0.55) | ERAP2ERAP1IL1RNPOLBCTSK | |
| SCHEMBL11856676 | 0.87 | LCK (0.49) | ERAP2ERAP1IL1RNPOLBLCK | |
| SCHEMBL11854644 | 0.87 | LCK (0.60) | ERAP2ERAP1IL1RNLCK | |
| SCHEMBL11858061 | 0.84 | ACE (0.48) | POLBTACR1LCKMMEANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3939253-A | Novel, transient pro-drug forms of l-dopa useful in the treatment of parkinson's disease | INTERX RESEARCH CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |