Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 19/20 | 0.45 |
| ▸ | HTR2A | P28223 | 17/20 | 0.45 |
| ▸ | HRH1 | P35367 | 8/20 | 0.45 |
| ▸ | DRD2 | P14416 | 6/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.39 |
| ▸ | HTR7 | P34969 | 5/20 | 0.39 |
| ▸ | DRD3 | P35462 | 5/20 | 0.39 |
| ▸ | DRD1 | P21728 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11841207 | 0.96 | HTR2C (0.44) | HTR2CHTR2AHRH1DRD2ADRA2A | |
| SCHEMBL11845578 | 0.83 | NPSR1 (0.40) | HTR2CHTR2AHRH1KDM4EUSP2 | |
| SCHEMBL11845059 | 0.81 | PGR (0.38) | HTR2AHRH1KDM4EUSP2MAPT | |
| SCHEMBL11843939 | 0.79 | KDM4E (0.38) | KDM4EUSP2MAPTTSHR | |
| SCHEMBL11847447 | 0.71 | TSHR (0.46) | KDM4EUSP2MAPTTSHR | |
| SCHEMBL11845163 | 0.70 | KDM4E (0.41) | KDM4EUSP2MAPTTSHR | |
| SCHEMBL11855903 | 0.69 | KDM4E (0.43) | HTR2CHTR2AHRH1DRD2ADRA2A | |
| SCHEMBL11845266 | 0.68 | CYP1A2 (0.42) | HTR2CHTR2AHRH1KDM4EUSP2 | |
| SCHEMBL11841202 | 0.68 | KDM4E (0.48) | KDM4EUSP2MAPTTSHR | |
| SCHEMBL11843347 | 0.67 | USP2 (0.44) | HTR2CHTR2AHRH1KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3980788-A | XANTHENYL COMPOUNDS | SMITHKLINE CORPORATION (US) | 1976-09-14 | — | — | US | disclosed |