Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11852623 | 0.91 | CHRM2 (0.41) | USP2KDM4EMAPTTSHRCHRM2 | |
| SCHEMBL11837989 | 0.89 | HSD17B1 (0.38) | USP2KDM4EMAPTTSHRCHRM2 | |
| SCHEMBL11855638 | 0.89 | KMT2A (0.40) | USP2KDM4EMAPTTSHRCHRM2 | |
| SCHEMBL11850300 | 0.87 | ALDH1A1 (0.42) | USP2KDM4EMAPTTSHRCHRM2 | |
| SCHEMBL11842265 | 0.86 | DRD1 (0.48) | USP2KDM4EMAPTTSHRHTR2A | |
| SCHEMBL11850634 | 0.86 | IRAK4 (0.37) | USP2KDM4EMAPTTSHRCHRM2 | |
| SCHEMBL11845227 | 0.83 | HTR2A (0.39) | USP2KDM4EMAPTTSHRHTR2A | |
| SCHEMBL11855903 | 0.82 | KDM4E (0.43) | USP2KDM4EMAPTTSHRCHRM2 | |
| SCHEMBL11851331 | 0.80 | HTR2A (0.39) | HTR2AHTR2CHRH1L3MBTL3MEN1 | |
| SCHEMBL11841936 | 0.79 | TSHR (0.42) | USP2KDM4EMAPTTSHRCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3980788-A | XANTHENYL COMPOUNDS | SMITHKLINE CORPORATION (US) | 1976-09-14 | — | — | US | claimed |
| US-3980788-A | XANTHENYL COMPOUNDS | SMITHKLINE CORPORATION (US) | 1976-09-14 | — | — | US | disclosed |