Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3638966 | 0.92 | TSHR (0.43) | TSHRSMN1; SMN2ALDH1A1FAAH | |
| SCHEMBL14423527 | 0.81 | TSHR (0.41) | TSHRSMN1; SMN2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL6247367 | 0.79 | — | — | |
| SCHEMBL3645617 | 0.78 | — | — | |
| SCHEMBL9015918 | 0.78 | TSHR (0.50) | TSHRSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8159493 | 0.78 | LMNA (0.48) | TSHRSMN1; SMN2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL9717978 | 0.78 | TSHR (0.39) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL9717975 | 0.78 | TSHR (0.39) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL18676850 | 0.76 | TSHR (0.38) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL617765 | 0.75 | TSHR (0.40) | TSHRSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3948728-A | Steroid-delta-isomerase | BOEHRINGER MANNHEIM G.M.B.H. (DT) | 1976-04-06 | — | — | US | claimed |