SCHEMBL617765

SCHEMBL617765

C=C[CH]C(CC=C)CCCC

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ALDH1A1 P00352 1/20 0.37
DNM1 Q05193 2/20 0.31
PLA2G2C Q5R387 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8043079 0.82 TSHR (0.54) TSHRSMN1; SMN2ALDH1A1DNM1
SCHEMBL3638966 0.82 TSHR (0.43) TSHRSMN1; SMN2ALDH1A1DNM1
SCHEMBL11648923 0.79 TSHR (0.39) TSHRSMN1; SMN2ALDH1A1DNM1
SCHEMBL1883787 0.78 TSHR (0.61) TSHRSMN1; SMN2ALDH1A1DNM1PLA2G2C
SCHEMBL3803410 0.77 TSHR (0.42) TSHRSMN1; SMN2DNM1
SCHEMBL11664850 0.77 TSHR (0.42) TSHRSMN1; SMN2DNM1
SCHEMBL9717978 0.77 TSHR (0.39) TSHRSMN1; SMN2ALDH1A1DNM1
SCHEMBL9717975 0.77 TSHR (0.39) TSHRSMN1; SMN2ALDH1A1DNM1
SCHEMBL16030557 0.76 TSHR (0.46) TSHRSMN1; SMN2ALDH1A1DNM1
SCHEMBL8676005 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 385 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3621955-B1 DEGRADABLE IMIDAZOLIUM OLIGOMER AND POLYMER FOR ANTIMICROBIAL APPLICATIONS AGENCY SCIENCE TECH & RES (SG) 2021-07-14 EP claimed
US-10927100-B2 Degradable imidazolium oligomer and polymer for antimicrobial applications AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2021-02-23 US claimed
US-20200181122-A1 Degradable Imidazolium Oligomer and Polymer for Antimicrobial Applications AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2020-06-11 US claimed
EP-3621955-A1 DEGRADABLE IMIDAZOLIUM OLIGOMER AND POLYMER FOR ANTIMICROBIAL APPLICATIONS Agency for Science, Technology and Research (SG) 2020-03-18 EP claimed
US-10562977-B2 Ligand-cytotoxic drug conjugate, preparation method thereof, and uses thereof SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD. (CN) 2020-02-18 US claimed
CN-110799500-A Degradable imidazolium oligomers and polymers for antimicrobial applications 新加坡科技研究局 2020-02-14 CN claimed
WO-2019004940-A1 DEGRADABLE IMIDAZOLIUM OLIGOMER AND POLYMER FOR ANTIMICROBIAL APPLICATIONS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2019-01-03 WO claimed
CN-107099016-A Trigger response chain fragmentation polymer 伊利诺伊大学董事会 2017-08-29 CN claimed
US-20170002090-A1 LIGAND-CYTOTOXIC DRUG CONJUGATE, PREPARATION METHOD THEREOF, AND USES THEREOF SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD. (CN) 2017-01-05 US claimed
EP-3100731-A1 LIGAND-CYTOTOXICITY DRUG CONJUGATE, PREPARATION METHOD THEREFOR, AND USES THEREOF Shanghai Hengrui Pharmaceutical Co., Ltd. (CN) 2016-12-07 EP claimed
WO-2001085694-A2 SUBSTITUTED DIAMIDE DERIVATIVES USEFUL AS MOTILIN ANTAGONISTS ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2001-11-15 WO claimed
EP-0915928-A4 SCORCH RESISTANT ADDITIVES FOR POLYURETHANE FOAMS CROMPTON CORP (US) 2001-08-29 EP claimed
US-6051620-A PROCESS FOR PRODUCING A POLYURETHANE FOAM BY REACTING A POLYISOCYANATE, POLYOL AND WATER; WHEREIN AT LEAST A PORTION OF THE POLYOL COMPRISES A POLYOL CONTAINING ESTER LINKAGES AND HYDRAZIDE LINKAGES; NONDISCOLORING CK WITCO CORPORATION 2000-04-18 US claimed
EP-0915928-A1 SCORCH RESISTANT ADDITIVES FOR POLYURETHANE FOAMS WITCO CORPORATION (US) 1999-05-19 EP claimed
WO-1998056849-A1 SCORCH RESISTANT ADDITIVES FOR POLYURETHANE FOAMS WITCO CORPORATION (US) 1998-12-17 WO claimed
EP-0247482-B1 HARDENED REAGENT COATINGS, AND PROCESSES FOR THE PREPARATION THEREOF MILES INC. (US) 1992-04-22 EP claimed
EP-0247482-A2 Hardened reagent coatings, and processes for the preparation thereof MILES INC. (US) 1987-12-02 EP claimed
US-4303752-A RELEASING AATP WITH SURFACTANTS WITHOUT LYSING CELL MEMBRANE OR WALL MINNESOTA MINING AND MANUFACTURING COMPANY, A CORP OF DE. 1981-12-01 US claimed
US-4233398-A Process for the hardening of photographic layers utilizing fast acting hardener and polysaccharide AGFA-GEVAERT, A.G. (DE) 1980-11-11 US claimed
US-4119464-A PRE-HARDENER OF COMPLEX-FORMING SALT OF ALUMINUM, CHROMIUM, OR ZIRCONIUM AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1978-10-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10927100-B2 Degradable imidazolium oligomer and polymer for antimicrobial applications NOD2, CFTR, PUF60 TSHR 4188/4885SMN1; SMN2 2413/4885ALDH1A1 3361/4885
US-20200181122-A1 Degradable Imidazolium Oligomer and Polymer for Antimicrobial Applications NOD2, CFTR, PUF60 TSHR 4188/4885SMN1; SMN2 2413/4885ALDH1A1 3361/4885
US-10562977-B2 Ligand-cytotoxic drug conjugate, preparation method thereof, and uses thereof LPXN, ADGRF1, LHCGR TSHR 609/4885SMN1; SMN2 4099/4885ALDH1A1 3429/4885
US-20170002090-A1 LIGAND-CYTOTOXIC DRUG CONJUGATE, PREPARATION METHOD THEREOF, AND USES THEREOF LPXN, ADGRF1, LHCGR TSHR 609/4885SMN1; SMN2 4099/4885ALDH1A1 3429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.