Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11841114 | 0.88 | TSHR (0.59) | TSHRALDH1A1LMNATRPA1GAA | |
| SCHEMBL11852039 | 0.82 | TSHR (0.62) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL11846556 | 0.79 | TSHR (0.50) | TSHRALDH1A1 | |
| SCHEMBL2494160 | 0.77 | TSHR (0.67) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL11842041 | 0.77 | TSHR (0.60) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL3013723 | 0.76 | CES1 (0.63) | ACHEALDH1A1TRPA1GAATP53 | |
| SCHEMBL2493279 | 0.75 | TSHR (0.83) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL11850067 | 0.75 | TSHR (0.53) | TSHRALDH1A1LMNAGAAGFER | |
| Maleic Acid SCHEMBL11840695 | 0.74 | TSHR (0.54) | TSHRALDH1A1LMNAMEN1KMT2A | |
| Fumaric Acid SCHEMBL11840713 | 0.74 | TSHR (0.54) | TSHRALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3969506-A | BRONCHODILATOR | SANDOZ, INC. (US) | 1976-07-13 | — | — | US | disclosed |