Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11846556 | 0.93 | TSHR (0.50) | TSHRDNMT1RAD52UHRF1DRD2 | |
| SCHEMBL11477847 | 0.78 | TSHR (0.56) | TSHRDNMT1RAD52UHRF1DRD2 | |
| SCHEMBL11852039 | 0.77 | TSHR (0.62) | TSHRDNMT1RAD52UHRF1GAA | |
| SCHEMBL11852580 | 0.75 | TSHR (0.54) | TSHRDNMT1RAD52UHRF1GAA | |
| SCHEMBL9533673 | 0.75 | TSHR (0.54) | TSHRDNMT1RAD52UHRF1DRD2 | |
| SCHEMBL11846561 | 0.75 | TSHR (0.54) | TSHRDNMT1RAD52UHRF1GAA | |
| SCHEMBL11848745 | 0.75 | TSHR (0.57) | TSHRGAAGFERLMNAALDH1A1 | |
| SCHEMBL2494160 | 0.74 | TSHR (0.67) | TSHRDNMT1RAD52UHRF1GAA | |
| SCHEMBL9532198 | 0.74 | TSHR (0.53) | TSHRDNMT1RAD52UHRF1GAA | |
| SCHEMBL11807301 | 0.74 | ALDH1A1 (0.52) | TSHRGFERLMNAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3969506-A | BRONCHODILATOR | SANDOZ, INC. (US) | 1976-07-13 | — | — | US | disclosed |