Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 3/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | EGFR | P00533 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | FYN | P06241 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | YARS1 | P54577 | 2/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11860286 | 0.94 | EGFR (0.55) | LCKALOX15KDM4ERECQLHIF1A | |
| SCHEMBL11852840 | 0.94 | EGFR (0.55) | LCKALOX15KDM4ERECQLHIF1A | |
| SCHEMBL11856676 | 0.91 | LCK (0.49) | LCKALOX15KDM4ERECQLHIF1A | |
| SCHEMBL11853539 | 0.91 | PPID (0.50) | LCKALOX15KDM4ERECQLHIF1A | |
| SCHEMBL11849660 | 0.90 | LCK (0.65) | LCKALOX15KDM4ERECQLHIF1A | |
| Hydrochloric Acid SCHEMBL11684930 | 0.89 | LCK (0.64) | LCKALOX15KDM4ERECQLHIF1A | |
| SCHEMBL11853292 | 0.86 | LCK (0.49) | LCKALOX15KDM4ERECQLHIF1A | |
| SCHEMBL27824407 | 0.86 | LNPEP (0.53) | SLC7A5YARS1ERAP2LNPEPERAP1 | |
| SCHEMBL4662496 | 0.86 | LNPEP (0.53) | SLC7A5YARS1ERAP2LNPEPERAP1 | |
| SCHEMBL27338458 | 0.85 | LCK (0.53) | LCKALOX15KDM4ERECQLHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3939253-A | Novel, transient pro-drug forms of l-dopa useful in the treatment of parkinson's disease | INTERX RESEARCH CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |