Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27338457 | 0.91 | LCK (0.64) | LCKALOX15ALOX12HSD17B10ALDH1A1 | |
| SCHEMBL11853292 | 0.86 | LCK (0.49) | LCKEGFRALOX15ALOX12HSD17B10 | |
| SCHEMBL27338453 | 0.86 | ACE (0.57) | LCKEGFRALOX15ALOX12HSD17B10 | |
| SCHEMBL11850734 | 0.85 | LCK (0.53) | LCKEGFRALOX15ALOX12HSD17B10 | |
| SCHEMBL11856676 | 0.83 | LCK (0.49) | LCKEGFRALOX15ALOX12HSD17B10 | |
| SCHEMBL11854802 | 0.82 | LCK (0.55) | LCKEGFRALOX15ALOX12HSD17B10 | |
| SCHEMBL21834064 | 0.81 | LCK (0.53) | LCKEGFRALOX15ALOX12HSD17B10 | |
| SCHEMBL14617725 | 0.81 | LCK (0.53) | LCKEGFRALOX15ALOX12HSD17B10 | |
| SCHEMBL15275678 | 0.80 | LCK (0.52) | LCKEGFRALOX15ALOX12HSD17B10 | |
| SCHEMBL11852840 | 0.80 | EGFR (0.55) | LCKEGFRALOX15HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240216469-A1 | SYNTHETIC TISSUE BARRIERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-07-04 | — | — | US | disclosed |
| US-20240216469-A1 | SYNTHETIC TISSUE BARRIERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240216469-A1 | SYNTHETIC TISSUE BARRIERS AND USES THEREOF | MMP1, PGF, CD68 | LCK 2030/4885EGFR 1449/4885ALOX15 619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.