Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 9/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11851924 | 1.00 | TAS2R14 (0.45) | TAS2R14KIF11ARPTPN1PTPN6 | |
| SCHEMBL11861242 | 0.83 | TAS2R14 (0.43) | TAS2R14ARPTPN1PTPN6PTPN11 | |
| SCHEMBL11856704 | 0.83 | TAS2R14 (0.52) | TAS2R14KIF11ARPTPN1PTPN6 | |
| SCHEMBL11861236 | 0.83 | TAS2R14 (0.43) | TAS2R14ARPTPN1PTPN6PTPN11 | |
| SCHEMBL11856710 | 0.83 | TAS2R14 (0.52) | TAS2R14KIF11ARPTPN1PTPN6 | |
| SCHEMBL11852621 | 0.83 | KIF11 (0.41) | TAS2R14KIF11ARPTPN1PTPN6 | |
| SCHEMBL11852613 | 0.83 | KIF11 (0.41) | TAS2R14KIF11ARPTPN1PTPN6 | |
| SCHEMBL11860522 | 0.77 | TAS2R14 (0.52) | TAS2R14PTPN1PTPN6PTPN11ALDH1A1 | |
| SCHEMBL11860518 | 0.77 | TAS2R14 (0.52) | TAS2R14PTPN1PTPN6PTPN11ALDH1A1 | |
| SCHEMBL17197622 | 0.73 | TAS2R14 (0.52) | TAS2R14KIF11ARPTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3976633-A | ANORECTIC, ANTIOBESITY | SMITHKLINE CORPORATION (US) | 1976-08-24 | — | — | US | claimed |
| US-3976633-A | ANORECTIC, ANTIOBESITY | SMITHKLINE CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |
| US-3976633-A | ANORECTIC, ANTIOBESITY | SMITHKLINE CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |