Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 6/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11858467 | 0.82 | ADRB2 (0.45) | ADRB2ADRB1KDM4EPABPC1ADRB3 | |
| SCHEMBL11849771 | 0.77 | ADRB2 (0.52) | ADRB2ADRB1KDM4EADRB3ADRA2A | |
| SCHEMBL11848246 | 0.77 | KDM4E (0.48) | ADRB2ADRB1KDM4EPABPC1ADRB3 | |
| SCHEMBL11848941 | 0.74 | ADRB2 (0.66) | ADRB2ADRB1KDM4EADRB3ADRA1A | |
| SCHEMBL11850645 | 0.73 | KMT2A (0.50) | KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11848932 | 0.73 | ADRB2 (0.64) | ADRB2ADRB1KDM4EADRB3ADRA1A | |
| SCHEMBL9768074 | 0.73 | ADRB2 (0.63) | ADRB2ADRB1KDM4EADRB3NPSR1 | |
| Hydrochloric Acid SCHEMBL11850641 | 0.73 | KMT2A (0.52) | KDM4ENPSR1SMN1; SMN2 | |
| SCHEMBL6925470 | 0.72 | GLA (0.46) | ADRB2ADRB1KDM4EADRB3NPSR1 | |
| Norbudrine SCHEMBL2732733 | 0.71 | ADRB2 (0.65) | ADRB2ADRB1KDM4EADRB3NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3976695-A | Halogen substituted α-(aminoalkyl)-3,4-dihydroxybenzyl alcohols | SMITHKLINE CORPORATION (US) | 1976-08-24 | — | — | US | claimed |
| US-3976695-A | Halogen substituted α-(aminoalkyl)-3,4-dihydroxybenzyl alcohols | SMITHKLINE CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |