Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 10/20 | 0.65 |
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | MTOR | P42345 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.58 |
| ▸ | DRD2 | P14416 | 3/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Norbudrine SCHEMBL29387737 | 1.00 | ADRB2 (0.65) | ADRB2MAPTKDM4ETDP1ADRB1 | |
| SCHEMBL9768074 | 0.95 | ADRB2 (0.63) | ADRB2MAPTKDM4ETDP1ADRB1 | |
| SCHEMBL4868791 | 0.81 | ADRB2 (0.87) | ADRB2KDM4ETDP1ADRB1TSHR | |
| Methane SCHEMBL5000046 | 0.80 | ADRB2 (0.85) | ADRB2KDM4ETDP1ADRB1TSHR | |
| SCHEMBL4868323 | 0.79 | ADRB2 (1.00) | ADRB2TDP1ADRB1TSHRCYP1A2 | |
| SCHEMBL4868288 | 0.79 | ADRB2 (1.00) | ADRB2TDP1ADRB1TSHRCYP1A2 | |
| SCHEMBL19330018 | 0.79 | KDM4E (0.63) | ADRB2KDM4ETDP1ADRB1ADRB3 | |
| SCHEMBL11701217 | 0.79 | ADRB2 (0.54) | ADRB2KDM4EMEN1KMT2ATSHR | |
| SCHEMBL11882698 | 0.78 | KDM4E (0.55) | ADRB2KDM4EADRB1ADRB3 | |
| SCHEMBL11669969 | 0.78 | ADRB2 (0.54) | ADRB2KDM4EADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190125699-A1 | TREATMENT OF CONNECTIVE TISSUE DISEASES OF THE SKIN | CIPHER PHARMACEUTICALS INC. (CA) | 2019-05-02 | — | — | US | claimed |
| US-20180193209-A1 | A POLYMER PRODUCT AND PREPARATION THEROF | SINGAPORE HEALTH SERVICES PTE LTD. (SG) | 2018-07-12 | — | — | US | claimed |
| EP-3319779-A1 | A POLYMER PRODUCT AND PREPARATION THEREOF | Singapore Health Services Pte Ltd (SG) | 2018-05-16 | — | — | EP | claimed |
| CN-108025477-A | Polymer products and their preparation | 新加坡保健服务集团 | 2018-05-11 | — | — | CN | claimed |
| US-20130237607-A1 | TREATMENT OF CONNECTIVE TISSUE DISEASES OF THE SKIN | ASTION DEVELOPMENT A/S (DK) | 2013-09-12 | — | — | US | claimed |
| EP-1719507-B1 | Beta-2 adrenoceptor agonists for treating connective tissue diseases of the skin | ASTION DEV AS (DK) | 2010-07-14 | — | — | EP | claimed |
| CN-101330905-A | Freeze-drying process and products obtained thereby | SCIDOSE LLC (US) | 2008-12-24 | — | — | CN | claimed |
| CN-101203214-A | Beta-2 adrenoceptor agonists for treating connective tissue diseases of the skin | ASTION DEV AS (DK) | 2008-06-18 | — | — | CN | claimed |
| WO-2006108424-A9 | BETA-2 ADRENOCEPTOR AGONISTS FOR TREATING CONNECTIVE TISSUE DISEASES OF THE SKIN | ASTION DEV AS (DK) | 2007-08-09 | — | — | WO | claimed |
| EP-1719507-A1 | Beta-2 adrenoceptor agonists for treating connective tissue diseases of the skin | Astion Development A/S (DK) | 2006-11-08 | — | — | EP | claimed |
| WO-2006108424-A2 | BETA-2 ADRENOCEPTOR AGONISTS FOR TREATING CONNECTIVE TISSUE DISEASES OF THE SKIN | ASTION PHARMA A/S (DK) | 2006-10-19 | — | — | WO | claimed |
| US-20060235048-A1 | Treatment of connective tissue diseases of the skin | ASTION DEVELOPMENT A/S | 2006-10-19 | — | — | US | claimed |
| WO-2019190402-A1 | BIOCOMPATIBLE OPHTHALMIC DEVICE | SINGAPORE HEALTH SERVICES PTE LTD (SG) | 2019-10-03 | — | — | WO | disclosed |
| US-20190125699-A1 | TREATMENT OF CONNECTIVE TISSUE DISEASES OF THE SKIN | CIPHER PHARMACEUTICALS INC. (CA) | 2019-05-02 | — | — | US | disclosed |
| US-20180193209-A1 | A POLYMER PRODUCT AND PREPARATION THEROF | SINGAPORE HEALTH SERVICES PTE LTD. (SG) | 2018-07-12 | — | — | US | disclosed |
| EP-3319779-A1 | A POLYMER PRODUCT AND PREPARATION THEREOF | Singapore Health Services Pte Ltd (SG) | 2018-05-16 | — | — | EP | disclosed |
| US-6264917-B1 | MIXTURE OF GAS FILLED MICROBUBBLES AND RELEASING AGENT | NYCOMED IMAGING AS (NO) | 2001-07-24 | — | — | US | disclosed |
| US-6261537-B1 | TARGETS AND ULTRASOUND DIAGNOSIS OF ACTIVE MATERIALS, AQUEOUS CARRIER LIQUIDS, CARRIERS AND FILM FORMING SURFACTANT PHOSPHATIDES | NYCOMED IMAGING AS (NO) | 2001-07-17 | — | — | US | disclosed |
| US-4011258-A | ETHANOLAMINES | AKTIEBOLAGET DRACO (SW) | 1977-03-08 | — | — | US | disclosed |
| US-3937838-A | BRONCHODILATORS, DIHYDROXYPHENYL ETHANOLAMINES | AKTIEBOLAGET DRACO (SW) | 1976-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130237607-A1 | TREATMENT OF CONNECTIVE TISSUE DISEASES OF THE SKIN | ADRB2, ADRB1, ADRA2A | ADRB2 1/4885MAPT 3107/4885KDM4E 2292/4885 |
| US-20060235048-A1 | Treatment of connective tissue diseases of the skin | ADRB2, ADRB1, ADRA2A | ADRB2 1/4885MAPT 3107/4885KDM4E 2292/4885 |
| US-20190125699-A1 | TREATMENT OF CONNECTIVE TISSUE DISEASES OF THE SKIN | ADRB2, ADRB1, ADRA2A | ADRB2 1/4885MAPT 3107/4885KDM4E 2292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.