SCHEMBL11854005

SCHEMBL11854005

O=S(=O)(O)Oc1ccc(Cc2ccc(O)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STS P08842 1/20 0.55
ESR1 P03372 3/20 0.54
ESR2 Q92731 3/20 0.54
PTPN1 P18031 1/20 0.50
CISD1 Q9NZ45 1/20 0.49
ELANE P08246 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
GAA P10253 2/20 0.40
GLA P06280 1/20 0.40
CALM1 P0DP23 1/20 0.39
APP P05067 1/20 0.39
PKM P14618 1/20 0.39
LMNA P02545 1/20 0.39
ALDH1A1 P00352 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
THRB P10828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL232089 0.88 CISD1 (0.58) ESR1ESR2CISD1ELANECA12
Lithium SCHEMBL17969202 0.86 CISD1 (0.56) ESR1ESR2CISD1ELANECA12
Potassium SCHEMBL565329 0.86 CISD1 (0.56) ESR1ESR2CISD1ELANECA12
SCHEMBL23094113 0.85 CA12 (0.55) STSCA12CA1CA2CA9
Formaldehyde SCHEMBL7924386 0.84 CISD1 (0.55) ESR1ESR2CISD1ELANECA12
SCHEMBL5871758 0.83 STS (0.81) STSESR1ESR2PTPN1CA12
Sulfuric Acid SCHEMBL11854002 0.81 ESR1 (0.74) ESR1ESR2PTPN1CA12CA1
Benzoquinone SCHEMBL11308710 0.80 CISD1 (0.51) ESR1ESR2CISD1ELANECA12
SCHEMBL11853686 0.80 LMNA (0.54) CA12CA1CA2CA9LMNA
Sulfuric Acid SCHEMBL11847363 0.79 ESR1 (0.70) ESR1ESR2PTPN1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3932481-A ANTILIPEMIC SHANDOZ, INC. (US) 1976-01-13 US disclosed