Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 8/20 | 0.81 |
| ▸ | CA2 | P00918 | 9/20 | 0.59 |
| ▸ | CA9 | Q16790 | 9/20 | 0.59 |
| ▸ | CA1 | P00915 | 8/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2501211 | 0.90 | STS (1.00) | STSCA2CA9CA1CA12 | |
| SCHEMBL28436327 | 0.86 | CA2 (0.73) | STSCA2CA9CA1 | |
| SCHEMBL11854005 | 0.83 | STS (0.55) | STSCA2CA9CA1CA12 | |
| SCHEMBL6800066 | 0.82 | CA2 (0.68) | STSCA2CA9CA1CA12 | |
| SCHEMBL6801523 | 0.80 | CA2 (0.66) | STSCA2CA9CA1CA12 | |
| Sulfuric Acid SCHEMBL11854002 | 0.75 | ESR1 (0.74) | CA2CA9CA1CA12ESR1 | |
| SCHEMBL18220792 | 0.74 | ESR1 (0.64) | STSCA2ESR1ESR2PTPN1 | |
| Sulfuric Acid SCHEMBL11847363 | 0.73 | ESR1 (0.70) | CA2CA9CA1CA12ESR1 | |
| SCHEMBL5488305 | 0.73 | ESR1 (0.70) | ESR1ESR2PTPN1 | |
| SCHEMBL12804905 | 0.73 | ESR1 (0.70) | ESR1ESR2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7119081-B2 | Oestrogen-17-sulphamates as inhibitors of steroid sulphatase | STERIX LIMITED (GB) | 2006-10-10 | — | — | US | disclosed |