Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | IARS1 | P41252 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11853292 | 0.92 | LCK (0.49) | LCKALOX15ALOX12HSD17B10ALDH1A1 | |
| SCHEMBL11859267 | 0.88 | ACE (0.55) | LCKALOX15ALOX12HSD17B10ALDH1A1 | |
| SCHEMBL11859253 | 0.88 | ACE (0.55) | LCKALOX15ALOX12HSD17B10ALDH1A1 | |
| SCHEMBL11858061 | 0.87 | ACE (0.48) | LCKTSHRPOLBEGFRMME | |
| SCHEMBL27338709 | 0.87 | TSHR (0.59) | TSHRHSD17B10ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL27338457 | 0.85 | LCK (0.64) | LCKTSHRALOX15ALOX12HSD17B10 | |
| SCHEMBL11849660 | 0.84 | LCK (0.65) | LCKTSHRALOX15HSD17B10ALDH1A1 | |
| SCHEMBL4127653 | 0.83 | LCK (0.56) | LCKTSHRALOX15HSD17B10ALDH1A1 | |
| SCHEMBL4127657 | 0.83 | LCK (0.56) | LCKTSHRALOX15HSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11684930 | 0.83 | LCK (0.64) | LCKTSHRALOX15HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3939253-A | Novel, transient pro-drug forms of l-dopa useful in the treatment of parkinson's disease | INTERX RESEARCH CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |