Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.47 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4127653 | 1.00 | LCK (0.56) | LCKHSD17B10TSHRALDH1A1THRB | |
| Hydrochloric Acid SCHEMBL4116808 | 0.99 | LCK (0.55) | LCKHSD17B10TSHRALDH1A1THRB | |
| Hydrochloric Acid SCHEMBL4116801 | 0.99 | LCK (0.55) | LCKHSD17B10TSHRALDH1A1THRB | |
| SCHEMBL11859518 | 0.83 | LCK (0.59) | LCKHSD17B10TSHRALDH1A1THRB | |
| SCHEMBL11850273 | 0.83 | LCK (0.59) | LCKHSD17B10TSHRALDH1A1THRB | |
| SCHEMBL11854079 | 0.83 | LCK (0.59) | LCKHSD17B10TSHRALDH1A1THRB | |
| SCHEMBL11849660 | 0.81 | LCK (0.65) | LCKHSD17B10TSHRALDH1A1THRB | |
| Hydrochloric Acid SCHEMBL11684930 | 0.80 | LCK (0.64) | LCKHSD17B10TSHRALDH1A1THRB | |
| SCHEMBL11854644 | 0.80 | LCK (0.60) | LCKHSD17B10TSHRALDH1A1THRB | |
| SCHEMBL15976476 | 0.78 | LCK (0.71) | LCKHSD17B10TSHRALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036525-A1 | Non-Natural Amino Acid Derivatives | POXIMAGEN LTD. (GB) | 2009-02-05 | — | — | US | disclosed |
| US-20090036525-A1 | Non-Natural Amino Acid Derivatives | POXIMAGEN LTD. (GB) | 2009-02-05 | — | — | US | disclosed |
| EP-1981839-A1 | NON-NATURAL AMINO ACID DERIVATIVES | Proximagen Ltd. (GB) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007091018-A1 | NON-NATURAL AMINO ACID DERIVATIVES | PROXIMAGEN LTD. (GB) | 2007-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036525-A1 | Non-Natural Amino Acid Derivatives | CHRNA6, PARK7, CHRNA7 | LCK 3375/4885HSD17B10 2004/4885TSHR 294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.