Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 11/20 | 0.48 |
| ▸ | MME | P08473 | 8/20 | 0.48 |
| ▸ | CPA1 | P15085 | 7/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 7/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11853292 | 0.88 | LCK (0.49) | ACEMMECPA1ACE2POLB | |
| SCHEMBL11854079 | 0.87 | LCK (0.59) | ACEMMECPA1ACE2POLB | |
| SCHEMBL11855613 | 0.85 | LCK (0.52) | ACEMMEPOLBTACR1LCK | |
| SCHEMBL11859267 | 0.85 | ACE (0.55) | ACEMMECPA1ACE2POLB | |
| SCHEMBL11859253 | 0.85 | ACE (0.55) | ACEMMECPA1ACE2POLB | |
| SCHEMBL11859692 | 0.84 | ERAP2 (0.49) | MMEPOLBTACR1LCKANPEP | |
| SCHEMBL1270964 | 0.84 | ACE (0.45) | ACEMMECPA1ACE2POLB | |
| SCHEMBL11861185 | 0.84 | YARS1 (0.53) | ACEMMEPOLBTACR1LCK | |
| SCHEMBL11857396 | 0.84 | YARS1 (0.53) | ACEMMEPOLBTACR1LCK | |
| SCHEMBL11852922 | 0.82 | ERAP2 (0.49) | MMELCKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3939253-A | Novel, transient pro-drug forms of l-dopa useful in the treatment of parkinson's disease | INTERX RESEARCH CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |