Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9413690 | 0.85 | MEN1 (0.40) | MEN1KMT2APKMSLC6A3TSHR | |
| SCHEMBL9153217 | 0.83 | SLC6A2 (0.38) | MEN1KMT2ASLC6A3SLC6A2LMNA | |
| SCHEMBL8921650 | 0.82 | ALDH1A1 (0.43) | MEN1KMT2APKMCTDSP1IDO1 | |
| SCHEMBL27373695 | 0.82 | MEN1 (0.40) | MEN1KMT2APKMCTDSP1SLC6A3 | |
| SCHEMBL11857164 | 0.81 | ALDH1A1 (0.37) | MEN1KMT2APKMCTDSP1TSHR | |
| SCHEMBL27372097 | 0.80 | SLC6A2 (0.36) | MEN1KMT2ASLC6A3CYP3A4MITF | |
| SCHEMBL12826050 | 0.78 | SLC6A2 (0.51) | MEN1KMT2APKMCTDSP1IDO1 | |
| SCHEMBL11854684 | 0.78 | MEN1 (0.56) | MEN1KMT2APKMCTDSP1SLC6A3 | |
| SCHEMBL11548405 | 0.77 | KMT2A (0.55) | MEN1KMT2APKMCTDSP1SLC6A3 | |
| SCHEMBL27788382 | 0.76 | MEN1 (0.50) | MEN1KMT2APKMCTDSP1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3991201-A | 1-(β-Aryl-β-R-ethyl)imidazoles as antimicrobial agents | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-11-09 | — | — | US | disclosed |