Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 9/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27391812 | 0.79 | PKM (0.59) | SLC6A2SLC6A4SLC6A3PKMCTDSP1 | |
| SCHEMBL2465315 | 0.78 | PKM (0.62) | SLC6A2SLC6A3PKMCTDSP1MEN1 | |
| SCHEMBL11854679 | 0.78 | MEN1 (0.48) | SLC6A2SLC6A3PKMCTDSP1MEN1 | |
| SCHEMBL11548405 | 0.78 | KMT2A (0.55) | SLC6A2SLC6A4SLC6A3PKMCTDSP1 | |
| SCHEMBL27788382 | 0.77 | MEN1 (0.50) | SLC6A2SLC6A3PKMCTDSP1MEN1 | |
| SCHEMBL27482765 | 0.77 | MEN1 (0.50) | SLC6A2SLC6A4SLC6A3PKMCTDSP1 | |
| Methyl Alcohol SCHEMBL27363776 | 0.76 | PKM (0.56) | SLC6A2SLC6A3PKMCTDSP1MEN1 | |
| SCHEMBL7428096 | 0.76 | MEN1 (0.55) | PKMCTDSP1MEN1KMT2AIDO1 | |
| SCHEMBL11312192 | 0.76 | MEN1 (0.51) | PKMCTDSP1MEN1KMT2AIDO1 | |
| SCHEMBL3126812 | 0.76 | MEN1 (0.51) | SLC6A2SLC6A3PKMCTDSP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2295413-A1 | Indazole compounds useful as protein kinase inhibitors | Vertex Pharmaceuticals Incorporated (US) | 2011-03-16 | — | — | EP | disclosed |