Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 14/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11848935 | 0.84 | PDK1 (0.40) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL11845972 | 0.82 | PDK1 (0.39) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL11843585 | 0.81 | ESR1 (0.41) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL15966371 | 0.78 | NOTUM (0.62) | NOTUM | |
| SCHEMBL22312090 | 0.73 | NOTUM (0.84) | NOTUMPKMALDH1A1 | |
| SCHEMBL29187809 | 0.72 | NOTUM (0.46) | NOTUMTP53PDK1PDK2PDK3 | |
| SCHEMBL24011117 | 0.71 | NOTUM (0.82) | NOTUMTP53PKMKDM4EALDH1A1 | |
| SCHEMBL5517952 | 0.71 | NOTUM (0.46) | NOTUMTP53 | |
| SCHEMBL698648 | 0.71 | NOTUM (0.62) | NOTUMTP53PDK1PDK2PDK3 | |
| SCHEMBL7973371 | 0.71 | NOTUM (0.60) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314693-B2 | Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge | RICOH COMPANY, LTD. (JP) | 2008-01-01 | — | — | US | disclosed |
| US-7314693-B2 | Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge | RICOH COMPANY, LTD. (JP) | 2008-01-01 | — | — | US | disclosed |
| US-3997542-A | 1-(Halogenated-acetyl)-1,2,3,4-tetrahydro-6-quinolinols and esters thereof | STERLING DRUG INC. (US) | 1976-12-14 | — | — | US | disclosed |