Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 13/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29862964 | 0.90 | NOTUM (0.69) | NOTUMCYP2D6CYP2C9POLB | |
| SCHEMBL5803030 | 0.90 | NOTUM (0.69) | NOTUMCYP2D6CYP2C9POLB | |
| SCHEMBL22312090 | 0.84 | NOTUM (0.84) | NOTUMTSHR | |
| SCHEMBL15966371 | 0.83 | NOTUM (0.62) | NOTUMSMN1; SMN2MEN1TSHRKMT2A | |
| SCHEMBL24011117 | 0.81 | NOTUM (0.82) | NOTUM | |
| SCHEMBL22312089 | 0.79 | NOTUM (0.63) | NOTUMSMN1; SMN2MEN1TSHRKMT2A | |
| SCHEMBL5366776 | 0.77 | NOTUM (0.55) | NOTUMCYP2D6CYP2C9 | |
| SCHEMBL2619231 | 0.76 | NOTUM (1.00) | NOTUMTSHRCYP2D6CYP2C9POLB | |
| SCHEMBL29216428 | 0.75 | NOTUM (0.58) | NOTUMSMN1; SMN2MEN1TSHRKMT2A | |
| SCHEMBL6402604 | 0.75 | TNKS (0.43) | MEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007412-A1 | ANTIVIRAL TETRAHYDROISICHINOLINSULFONAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-01 | — | — | WO | disclosed |