Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | METAP2 | P50579 | 2/20 | 0.43 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28557085 | 0.79 | HPGD (0.53) | HSD17B10ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL4899928 | 0.77 | HSD17B10 (0.55) | HSD17B10ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL29642615 | 0.77 | ALDH1A1 (0.42) | HSD17B10ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL17787466 | 0.77 | ALDH1A1 (0.42) | HSD17B10ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL38584 | 0.75 | TDP1 (0.41) | HSD17B10ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL29500990 | 0.75 | TDP1 (0.41) | HSD17B10ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL3333505 | 0.74 | CYP3A4 (0.57) | HSD17B10ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL11722688 | 0.74 | POLB (0.46) | HSD17B10ALDH1A1HPGDMEN1KMT2A | |
| Alpha-Naphthylisocyanate SCHEMBL374 | 0.72 | CYP1A2 (0.64) | HSD17B10ALDH1A1HPGDCYP1A2CYP2C19 | |
| SCHEMBL1661024 | 0.72 | HSD17B10 (0.63) | HSD17B10ALDH1A1HPGDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985711-A | Dicarboxylic compounds having 2,4-quinazolinedione rings and polyester resins derived therefrom | INSTITUT FRANCAIS DU PETROLE, DES CARBURANTS ET LUBRIFIANTS ET ENTREPRISE DE RECHERCHES ET D'ACTIVITIES PETROLIERES ELF (FR) | 1976-10-12 | — | — | US | disclosed |