Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17787466 | 0.81 | ALDH1A1 (0.42) | CYP3A4TSHRCYP2A6CYP1A2HPGD | |
| SCHEMBL29642615 | 0.81 | ALDH1A1 (0.42) | CYP3A4TSHRCYP2A6CYP1A2HPGD | |
| SCHEMBL28535587 | 0.80 | CYP3A4 (0.50) | CYP3A4TSHRCYP2A6CYP1A2HPGD | |
| SCHEMBL38584 | 0.79 | TDP1 (0.41) | CYP3A4TSHRCYP2A6CYP1A2HPGD | |
| SCHEMBL29500990 | 0.79 | TDP1 (0.41) | CYP3A4TSHRCYP2A6CYP1A2HPGD | |
| SCHEMBL995429 | 0.79 | CYP3A4 (0.56) | CYP3A4TSHRCYP1A2HPGDL3MBTL1 | |
| SCHEMBL14118175 | 0.79 | TSHR (0.54) | CYP3A4TSHRCYP2A6CYP1A2HPGD | |
| SCHEMBL11722688 | 0.78 | POLB (0.46) | CYP3A4TSHRCYP2A6CYP1A2HPGD | |
| SCHEMBL11716452 | 0.77 | CYP3A4 (0.39) | CYP3A4TSHRCYP2A6CYP1A2HPGD | |
| SCHEMBL3338003 | 0.77 | NCEH1 (0.42) | CYP3A4TSHRCYP2A6CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144698-A1 | SUBSTITUTED AZETIDINONES | DAIAMED (US) | 2010-06-10 | — | — | US | disclosed |
| US-20090143351-A1 | SUBSTITUTED AZETIDINONES | DAIAMED (US) | 2009-06-04 | — | — | US | disclosed |
| US-7501404-B2 | Substituted azetidinones | DAIMED (US) | 2009-03-10 | — | — | US | disclosed |
| EP-1871741-A2 | SUBSTITUTED AZETIDINONES | Daiamed, Inc. (US) | 2008-01-02 | — | — | EP | disclosed |
| US-20070105832-A1 | Substituted azetidinones | Cadrenal Therapeutics, Inc. | 2007-05-10 | — | — | US | disclosed |
| WO-2006108039-A2 | SUBSTITUTED AZETIDINONES | DAIAMED, INC. (US) | 2006-10-12 | — | — | WO | disclosed |
| CN-1192251-C | Extended wear ophthalmic lens | NOVARTIS AG (CH) | 2005-03-09 | — | — | CN | disclosed |
| CN-1180416-A | Extended wear ophthalmic lenses | CIBA GEIGY AG (CH) | 1998-04-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105832-A1 | Substituted azetidinones | F2R, CPA3, CFD | CYP3A4 795/4885TSHR 414/4885CYP2A6 577/4885 |
| US-20100144698-A1 | SUBSTITUTED AZETIDINONES | F2R, CPA3, CFD | CYP3A4 795/4885TSHR 414/4885CYP2A6 577/4885 |
| US-20090143351-A1 | SUBSTITUTED AZETIDINONES | F2R, CPA3, CFD | CYP3A4 795/4885TSHR 414/4885CYP2A6 577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.