Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11429589 | 0.78 | CYP2C9 (0.53) | CYP2C9HPGDSCNR2CNR1HPGD | |
| Ticrynafen SCHEMBL123608 | 0.77 | CYP2C9 (1.00) | CYP2C9HPGDSHPGDTSHRTDP1 | |
| Ticrynafen SCHEMBL30232637 | 0.77 | CYP2C9 (1.00) | CYP2C9HPGDSHPGDTSHRTDP1 | |
| SCHEMBL11427121 | 0.76 | CYP2C9 (0.57) | CYP2C9HPGDSHPGDTSHRNPC1 | |
| SCHEMBL11432610 | 0.76 | CYP2C9 (0.57) | CYP2C9HPGDSHPGDTSHRNPC1 | |
| SCHEMBL14419330 | 0.76 | CYP2C9 (0.71) | CYP2C9TSHRTDP1MAPTSLC6A9 | |
| SCHEMBL11426652 | 0.75 | THRA (0.51) | CYP2C9HPGDSCNR2HPGDTSHR | |
| SCHEMBL11442063 | 0.75 | POLB (0.53) | CYP2C9HPGDSCNR2CNR1HPGD | |
| SCHEMBL1614561 | 0.70 | TDP1 (0.64) | HPGDTSHRTDP1MAPTKMT2A | |
| SCHEMBL11435106 | 0.69 | CYP2C9 (0.69) | CYP2C9HPGDSHPGDTSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3958004-A | ADMINISTERING | MERCK & CO., INC. (US) | 1976-05-18 | — | — | US | disclosed |