Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | HPGDS | O60760 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | VNN1 | O95497 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11427121 | 0.84 | CYP2C9 (0.57) | CYP2C9HPGDSHPGDNPC1RAB9A | |
| SCHEMBL11442063 | 0.84 | POLB (0.53) | CYP2C9HPGDSHPGDNPC1RAB9A | |
| SCHEMBL11429589 | 0.84 | CYP2C9 (0.53) | CYP2C9HPGDSHPGDNPC1RAB9A | |
| SCHEMBL6724871 | 0.81 | THRA (0.57) | THRATHRBKMT2ACD69KDM4E | |
| SCHEMBL6728497 | 0.80 | THRA (0.61) | THRATHRBVNN1ALDH1A1MEN1 | |
| SCHEMBL11435428 | 0.76 | HPGD (0.45) | CYP2C9HPGDSHPGDNPC1RAB9A | |
| SCHEMBL11855656 | 0.75 | CYP2C9 (0.62) | CYP2C9HPGDSHPGDNPC1RAB9A | |
| SCHEMBL6725180 | 0.75 | THRB (0.55) | THRATHRBCYP2C9PTGS2ALDH1A1 | |
| SCHEMBL11432610 | 0.74 | CYP2C9 (0.57) | CYP2C9HPGDSHPGDNPC1RAB9A | |
| SCHEMBL14040248 | 0.70 | THRA (0.46) | THRATHRBTSHRKMT2ACD69 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4197309-A | AND THEIR OXIMES, USED TO INDUCE URICOSIC EFFECT WITHOUT DIURESIS | ALBERT ROLAND S.A. (FR) | 1980-04-08 | — | — | US | claimed |
| US-4197309-A | AND THEIR OXIMES, USED TO INDUCE URICOSIC EFFECT WITHOUT DIURESIS | ALBERT ROLAND S.A. (FR) | 1980-04-08 | — | — | US | disclosed |