Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 3/20 | 0.75 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.75 |
| ▸ | TTR | P02766 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | KDM5A | P29375 | 2/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.60 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.60 |
| ▸ | SIRT3 | Q9NTG7 | 9/20 | 0.59 |
| ▸ | THRA | P10827 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 2/20 | 0.57 |
| ▸ | KDM4A | O75164 | 1/20 | 0.56 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.56 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11843283 | 0.92 | CYP2C9 (0.67) | EYA3PTPN1TTRCYP2C9KDM5A | |
| SCHEMBL25389924 | 0.89 | EYA3 (0.82) | EYA3PTPN1TTRKDM5ANR1H4 | |
| SCHEMBL27992957 | 0.88 | EYA3 (0.80) | EYA3PTPN1TTRKDM5ANR1H4 | |
| SCHEMBL11850267 | 0.87 | CYP2C9 (0.82) | EYA3PTPN1TTRCYP2C9NR1H4 | |
| SCHEMBL1287970 | 0.86 | EYA3 (1.00) | EYA3PTPN1TTRCYP2C9KDM5A | |
| SCHEMBL28849127 | 0.86 | EYA3 (0.81) | EYA3PTPN1TTRKDM5ANR1H4 | |
| SCHEMBL31314614 | 0.85 | EYA3 (0.79) | EYA3PTPN1TTRKDM5ANR1H4 | |
| SCHEMBL3863077 | 0.85 | EYA3 (0.79) | EYA3PTPN1TTRKDM5ANR1H4 | |
| SCHEMBL31314615 | 0.85 | EYA3 (0.79) | EYA3PTPN1TTRKDM5ANR1H4 | |
| SCHEMBL31314577 | 0.85 | EYA3 (0.79) | EYA3PTPN1TTRKDM5ANR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4000281-A | VIRICIDES | RICHARDSON-MERRELL INC. (US) | 1976-12-28 | — | — | US | disclosed |