Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 6/20 | 0.61 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.61 |
| ▸ | FABP2 | P12104 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.61 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.61 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11489603 | 0.88 | LMNA (0.57) | AKR1C3AKR1C2LMNAPTGS1MEN1 | |
| SCHEMBL30986301 | 0.87 | LMNA (0.65) | AKR1C3AKR1C2LMNAPTGS1MEN1 | |
| SCHEMBL988019 | 0.87 | LMNA (0.65) | AKR1C3AKR1C2LMNAPTGS1MEN1 | |
| SCHEMBL11804390 | 0.84 | AKR1C3 (0.61) | AKR1C3AKR1C2LMNAPTGS1MEN1 | |
| SCHEMBL11990042 | 0.84 | AKR1C3 (0.60) | AKR1C3AKR1C2LMNAPTGS1MEN1 | |
| SCHEMBL8011500 | 0.84 | AKR1C3 (0.60) | AKR1C3AKR1C2LMNAPTGS1MEN1 | |
| SCHEMBL11868212 | 0.83 | AKR1C3 (0.63) | AKR1C3AKR1C2LMNAPTGS1MEN1 | |
| SCHEMBL11861696 | 0.82 | LMNA (0.67) | AKR1C3AKR1C2LMNAPTGS1MEN1 | |
| SCHEMBL11544423 | 0.81 | CYP2C19 (0.43) | AKR1C3AKR1C2LMNAPTGS1MEN1 | |
| SCHEMBL11855142 | 0.81 | TRPA1 (0.46) | AKR1C3AKR1C2LMNAPTGS1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3969419-A | ANTIPHLOGISTIC | BOEHRINGER INGELHEIM GMBH (DT) | 1976-07-13 | — | — | US | claimed |
| US-3969419-A | ANTIPHLOGISTIC | BOEHRINGER INGELHEIM GMBH (DT) | 1976-07-13 | — | — | US | disclosed |