Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL677886 | 0.93 | PARP10 (0.54) | PARP10KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL17995562 | 0.91 | CA1 (0.53) | PARP10KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL27454626 | 0.86 | PARP10 (0.56) | PARP10KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL20679845 | 0.86 | FFAR1 (0.49) | PARP10KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL12199140 | 0.85 | PARP10 (0.62) | PARP10KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL725405 | 0.84 | PARP10 (0.77) | PARP10KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL11354320 | 0.84 | MAPT (0.58) | PARP10KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL1546405 | 0.84 | PARP10 (0.61) | PARP10KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL8210785 | 0.84 | PARP10 (0.61) | PARP10KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL4905240 | 0.84 | KMT2A (0.62) | PARP10KMT2AMAPTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693888-B | A kind of thioxanthone visible light initiator and preparation method containing acrylate or methacrylate of polymerizable type | 武汉大学 | 2017-08-25 | — | — | CN | claimed |
| US-20160237023-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES | UNIVERSITÄT ZU KÖLN (DE) | 2016-08-18 | — | — | US | claimed |
| CN-105693888-A | Polymerizable type thioxanthone visible light initiator containing acrylate or methacrylate and preparation method | 武汉大学 | 2016-06-22 | — | — | CN | claimed |
| WO-2024189607-A1 | METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT | DIDENKO KIRILL (MX) | 2024-09-19 | — | — | WO | disclosed |
| EP-3049386-B9 | COMPOUNDS USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES | UNIV KOELN (DE) | 2020-11-18 | — | — | EP | disclosed |
| US-10793509-B2 | Compounds useful in the treatment of neoplastic diseases | UNIVERSITÄT ZU KOLN (DE) | 2020-10-06 | — | — | US | disclosed |
| US-10793509-B2 | Compounds useful in the treatment of neoplastic diseases | UNIVERSITÄT ZU KOLN (DE) | 2020-10-06 | — | — | US | disclosed |
| EP-3049386-B1 | COMPOUNDS USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES | UNIV KOELN (DE) | 2020-07-22 | — | — | EP | disclosed |
| CN-105693888-B | A kind of thioxanthone visible light initiator and preparation method containing acrylate or methacrylate of polymerizable type | 武汉大学 | 2017-08-25 | — | — | CN | disclosed |
| US-20160237023-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES | UNIVERSITÄT ZU KÖLN (DE) | 2016-08-18 | — | — | US | disclosed |
| US-20160237023-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES | UNIVERSITÄT ZU KÖLN (DE) | 2016-08-18 | — | — | US | disclosed |
| US-20160237023-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES | UNIVERSITÄT ZU KÖLN (DE) | 2016-08-18 | — | — | US | disclosed |
| CN-105693888-A | Polymerizable type thioxanthone visible light initiator containing acrylate or methacrylate and preparation method | 武汉大学 | 2016-06-22 | — | — | CN | disclosed |
| CN-105693888-A | Polymerizable type thioxanthone visible light initiator containing acrylate or methacrylate and preparation method | 武汉大学 | 2016-06-22 | — | — | CN | disclosed |
| WO-2015044177-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES | UNIVERSITÄT ZU KÖLN (DE) | 2015-04-02 | — | — | WO | disclosed |
| US-3956363-A | Substituted indenyl acetic acids | MERCK & CO., INC. (US) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160237023-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES | APC, BRCA1, VHL | PARP10 2240/4885KMT2A 3041/4885MAPT 1257/4885 |
| US-10793509-B2 | Compounds useful in the treatment of neoplastic diseases | APC, BRCA1, VHL | PARP10 2240/4885KMT2A 3041/4885MAPT 1257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.