SCHEMBL20679845

SCHEMBL20679845

O=C(Oc1ccc(C#Cc2ccccc2)cc1)c1ccc(CCl)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FFAR1 O14842 4/20 0.49
▸ PARP10 Q53GL7 1/20 0.49
▸ FFAR4 Q5NUL3 1/20 0.45
▸ PPARG P37231 1/20 0.45
▸ PPARA Q07869 1/20 0.45
▸ KMT2A Q03164 6/20 0.44
▸ MEN1 O00255 3/20 0.44
▸ TSHR P16473 1/20 0.43
▸ MAPT P10636 4/20 0.43
▸ TDP1 Q9NUW8 2/20 0.43
▸ ALDH1A1 P00352 2/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ PKM P14618 1/20 0.43
▸ KDM4E B2RXH2 1/20 0.42
▸ PRSS1 P07477 3/20 0.42
▸ TMPRSS2 O15393 1/20 0.42
▸ KLK1 P06870 1/20 0.42
▸ RAB9A P51151 1/20 0.41
▸ ACR P10323 1/20 0.41
▸ TMPRSS15 P98073 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11857748 0.86 PARP10 (0.59) PARP10KMT2AMEN1TSHRMAPT
SCHEMBL677886 0.86 PARP10 (0.54) PARP10KMT2AMEN1TSHRMAPT
SCHEMBL18561127 0.85 PARP10 (0.61) FFAR1PARP10PPARGPPARAKMT2A
SCHEMBL18561129 0.85 PARP10 (0.61) FFAR1PARP10PPARGPPARAKMT2A
SCHEMBL4361160 0.85 PARP10 (0.56) FFAR1PARP10KMT2AMEN1MAPT
SCHEMBL19168001 0.85 PARP10 (0.56) FFAR1PARP10KMT2AMEN1MAPT
SCHEMBL17995562 0.84 CA1 (0.53) PARP10KMT2AMEN1MAPTALDH1A1
SCHEMBL23866503 0.83 PARP10 (0.62) FFAR1PARP10KMT2AMEN1MAPT
SCHEMBL26038945 0.81 VCP (0.55) FFAR1PARP10KMT2AMEN1MAPT
SCHEMBL11354320 0.78 MAPT (0.58) PARP10KMT2AMEN1TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11702509-B2 Monomer, polymer, compensation film, optical film, and display device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-18 — — US disclosed
US-11702509-B2 Monomer, polymer, compensation film, optical film, and display device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-18 — — US disclosed
US-11702509-B2 Monomer, polymer, compensation film, optical film, and display device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-18 — — US disclosed
US-20200377659-A1 MONOMER, POLYMER, COMPENSATION FILM, OPTICAL FILM, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2020-12-03 — — US disclosed
US-20200377659-A1 MONOMER, POLYMER, COMPENSATION FILM, OPTICAL FILM, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2020-12-03 — — US disclosed
US-10808080-B2 Monomer, polymer, compensation film, optical film, and display device SAMSUNG ELECTRONICS CO, LTD. (KR) 2020-10-20 — — US disclosed
US-10808080-B2 Monomer, polymer, compensation film, optical film, and display device SAMSUNG ELECTRONICS CO, LTD. (KR) 2020-10-20 — — US disclosed
EP-3438156-B1 MONOMER, POLYMER, COMPENSATION FILM, OPTICAL FILM, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2020-04-22 — — EP disclosed
EP-3438156-A1 MONOMER, POLYMER, COMPENSATION FILM, OPTICAL FILM, AND DISPLAY DEVICE Samsung Electronics Co., Ltd. (KR) 2019-02-06 — — EP disclosed
CN-109305949-A Monomer, polymer, compensation film, optical film and display equipment 三星电子株式会社 2019-02-05 — — CN disclosed
US-20190031831-A1 MONOMER, POLYMER, COMPENSATION FILM, OPTICAL FILM, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-01-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190031831-A1 MONOMER, POLYMER, COMPENSATION FILM, OPTICAL FILM, AND DISPLAY DEVICE RAP1A, PYM1, COL1A1 FFAR1 1063/4885PARP10 400/4885FFAR4 2892/4885
US-20200377659-A1 MONOMER, POLYMER, COMPENSATION FILM, OPTICAL FILM, AND DISPLAY DEVICE PYM1, PADI1, COL1A1 FFAR1 1208/4885PARP10 362/4885FFAR4 3276/4885
US-11702509-B2 Monomer, polymer, compensation film, optical film, and display device PYM1, PADI1, COL1A1 FFAR1 1208/4885PARP10 362/4885FFAR4 3276/4885
US-10808080-B2 Monomer, polymer, compensation film, optical film, and display device RAP1A, PYM1, COL1A1 FFAR1 1063/4885PARP10 400/4885FFAR4 2892/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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