Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 1/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11860867 | 0.83 | EPHX1 (0.38) | TSHRKMT2AMEN1 | |
| SCHEMBL11866961 | 0.82 | MAPK1 (0.36) | MAPK1NQO2MTNR1AMTNR1BTSHR | |
| SCHEMBL11861382 | 0.82 | TSHR (0.35) | CYP2C19TSHRNFKB1 | |
| SCHEMBL11862740 | 0.81 | TSHR (0.35) | SIGMAR1TSHR | |
| SCHEMBL24333751 | 0.80 | SIGMAR1 (0.38) | SIGMAR1CYP2C19CYP1A2CYP3A4MAPK1 | |
| SCHEMBL11868753 | 0.79 | ACHE (0.34) | BCHETSHR | |
| SCHEMBL11861922 | 0.79 | HSD17B10 (0.39) | TSHRKMT2AMEN1 | |
| SCHEMBL11856678 | 0.77 | EPHX2 (0.33) | TSHR | |
| SCHEMBL11090 | 0.76 | SIGMAR1 (0.49) | SIGMAR1CYP2C19CYP1A2CYP3A4MAPK1 | |
| SCHEMBL11860686 | 0.76 | SIRT2 (0.31) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3937711-A | POLYMERIC STABILIZERS, POLYOLEFINS | CIBA-GEIGY CORPORATION (US) | 1976-02-10 | — | — | US | disclosed |