Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 2/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.64 |
| ▸ | KDM7A | Q6ZMT4 | 4/20 | 0.63 |
| ▸ | TTR | P02766 | 1/20 | 0.59 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.58 |
| ▸ | KDM5A | P29375 | 4/20 | 0.57 |
| ▸ | THRA | P10827 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
| ▸ | KDM4A | O75164 | 2/20 | 0.55 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1288046 | 0.89 | CYP2C19 (0.63) | EYA3PTPN1KDM7ATTRTHRB | |
| SCHEMBL11840655 | 0.88 | EYA3 (0.65) | EYA3PTPN1KDM7ATTRSIRT3 | |
| SCHEMBL10853515 | 0.88 | SIRT3 (0.60) | EYA3PTPN1KDM7ASIRT3KDM5A | |
| SCHEMBL10856948 | 0.87 | SIRT3 (0.59) | EYA3PTPN1KDM7ATTRSIRT3 | |
| SCHEMBL10854519 | 0.87 | SIRT3 (0.59) | EYA3PTPN1KDM7ATTRSIRT3 | |
| SCHEMBL11844885 | 0.86 | EYA3 (0.68) | EYA3PTPN1KDM7ATTRSIRT3 | |
| SCHEMBL11849394 | 0.85 | SIRT3 (0.56) | EYA3PTPN1KDM7ATTRSIRT3 | |
| SCHEMBL11843232 | 0.83 | EYA3 (0.77) | EYA3PTPN1KDM7ATTRSIRT3 | |
| SCHEMBL11851104 | 0.82 | KDM7A (0.57) | EYA3PTPN1KDM7ATTRSIRT3 | |
| SCHEMBL29736895 | 0.82 | EYA3 (0.76) | EYA3PTPN1KDM7ATTRSIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975537-A | SUBSTITUTED BENZOFURANS | SMITH KLINE (US) | 1976-08-17 | — | — | US | disclosed |