Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | PTGFR | P43088 | 1/20 | 0.30 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7543239 | 0.90 | ALDH1A1 (0.41) | TSHRALDH1A1EPHX1ALOX5TBXA2R | |
| SCHEMBL6237982 | 0.88 | ALDH1A1 (0.38) | TSHRALDH1A1EPHX1ALOX5TBXA2R | |
| SCHEMBL816628 | 0.82 | CYP1A2 (0.36) | ALDH1A1 | |
| SCHEMBL11735435 | 0.78 | GBA1 (0.39) | — | |
| SCHEMBL15922307 | 0.77 | TSHR (0.35) | TSHRALDH1A1EPHX1ALOX5TBXA2R | |
| SCHEMBL6237588 | 0.74 | EPHX1 (0.43) | TSHRALDH1A1EPHX1ALOX5PPARG | |
| SCHEMBL4879664 | 0.73 | CYP1A2 (0.30) | — | |
| SCHEMBL9352873 | 0.73 | — | — | |
| SCHEMBL6242175 | 0.71 | EPHX1 (0.40) | TSHRALDH1A1EPHX1ALOX5PTGER2 | |
| SCHEMBL11778677 | 0.70 | USP2 (0.39) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3937763-A | TETRAPOLYMER OF ETHYLENE-A-OLEFIN-HALONORBORNENE-NON-CONJUGATED POLYENES, DIENE RUBBER, BUTYL RUBBER | SUMITOMO CHEMICAL COMPANY, LTD. (JA) | 1976-02-10 | — | — | US | claimed |
| US-3937763-A | TETRAPOLYMER OF ETHYLENE-A-OLEFIN-HALONORBORNENE-NON-CONJUGATED POLYENES, DIENE RUBBER, BUTYL RUBBER | SUMITOMO CHEMICAL COMPANY, LTD. (JA) | 1976-02-10 | — | — | US | disclosed |