SCHEMBL7543239

SCHEMBL7543239

CCCCCCCCCCCCC1C2C=CC(C2)C1CCCCCCCCCCCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
EPHX1 P07099 1/20 0.39
ALOX5 P09917 1/20 0.37
TSHR P16473 2/20 0.36
THRB P10828 1/20 0.36
SLC22A1 O15245 1/20 0.35
PPARG P37231 2/20 0.33
TBXA2R P21731 1/20 0.33
PTGFR P43088 1/20 0.33
PTGER2 P43116 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
ALOX15 P16050 1/20 0.33
ALOX12 P18054 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HIF1A Q16665 1/20 0.33
HSD17B10 Q99714 1/20 0.33
GBA1 P04062 2/20 0.33
GLB1 P16278 1/20 0.33
GBA2 Q9HCG7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6237982 0.98 ALDH1A1 (0.38) ALDH1A1EPHX1ALOX5TSHRTHRB
SCHEMBL816628 0.91 CYP1A2 (0.36) ALDH1A1GLB1CYP1A2
SCHEMBL11735435 0.86 GBA1 (0.39) GBA1GLB1GBA2
SCHEMBL15922307 0.86 TSHR (0.35) ALDH1A1EPHX1ALOX5TSHRPPARG
SCHEMBL6237588 0.82 EPHX1 (0.43) ALDH1A1EPHX1ALOX5TSHRTHRB
SCHEMBL15901201 0.80 ALOX5 (0.39) ALDH1A1ALOX5TSHRPPARGTBXA2R
SCHEMBL11595634 0.79 MGLL (0.46) ALDH1A1PPARGTP53SMN1; SMN2CYP1A2
SCHEMBL11675160 0.79 PTGS1 (0.63) ALDH1A1TP53SMN1; SMN2
SCHEMBL11676768 0.79 MGLL (0.54) ALDH1A1TSHRTP53SMN1; SMN2HSD17B10
SCHEMBL11595729 0.79 MGLL (0.46) ALDH1A1PPARGTP53SMN1; SMN2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4612126-A1 COMPOSITIONS INCLUDING A MIXTURE OF ISOMERS OF ITACONIMIDE NORBORNENE AND CITRACONIMIDE NORBORNENE 3M Innovative Properties Company (US) 2025-09-10 EP disclosed
US-20240279251-A1 Monomer, Polymerizable Composition, and Polymers Derived Therefrom 3M INNOVATIVE PROPERTIES COMPANY 2024-08-22 US disclosed
WO-2024095078-A1 COMPOSITIONS INCLUDING A MIXTURE OF ISOMERS OF ITACONIMIDE NORBORNENE AND CITRACONIMIDE NORBORNENE 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-05-10 WO disclosed
WO-2022238774-A1 MONOMER, POLYMERIZABLE COMPOSITION, AND POLYMERS DERIVED THEREFROM 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-11-17 WO disclosed
WO-2022118175-A1 CURABLE COMPOSITIONS, COMPOSITE FOAM, METHOD OF MAKING THE SAME, AND ARTICLE INCLUDING THE SAME 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-06-09 WO disclosed
US-6476240-B2 POLYMERS DERIVED FROM AN UNSATURATED FUSED CYCLIC HYDROCARBON (SUCH AS PERHYDRO-2,3-DIDEHYDRO-1,4:5,8-DIMETHANONAPHTHALENE) JOINED BY A LINKER TO AN ESTER GROUP HAVING ONE OR TWO PROTECTED HYDROXYLS; USE AS PHOTORESIST WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2002-11-05 US disclosed
US-20020042531-A1 Polymers derived from an unsaturated fused cyclic hydrocarbon (such as perhydro-2,3-didehydro-1,4:5,8-dimethanonaphthalene) joined by a linker to an ester group having one or two protected hydroxyls; use as photoresist WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2002-04-11 US disclosed
US-6331602-B1 Monomer and a polymer obtained therefrom WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2001-12-18 US disclosed
US-6160068-A Monomer and a polymer obtained therefrom WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2000-12-12 US disclosed
US-6143472-A Resist composition and a method for formation of a pattern using the composition WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2000-11-07 US disclosed
EP-0918048-A1 A novel monomer and a polymer obtained therefrom Wako Pure Chemical Industries, Ltd. (JP) 1999-05-26 EP disclosed
US-4033982-A REACTING NORBORNENES WITH SULFUR GENERAL ELECTRIC COMPANY (US) 1977-07-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240279251-A1 Monomer, Polymerizable Composition, and Polymers Derived Therefrom PBRM1, CARM1, WASF2 ALDH1A1 2168/4885EPHX1 4033/4885ALOX5 926/4885
US-20020042531-A1 Polymers derived from an unsaturated fused cyclic hydrocarbon (such as perhydro-2,3-didehydro-1,4:5,8-dimethanonaphthalene) joined by a linker to an ester group having one or two protected hydroxyls; use as photoresist AHR, DHCR24, FPR1 ALDH1A1 519/4885EPHX1 250/4885ALOX5 110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.