Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 11/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.55 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.55 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11866688 | 0.93 | TTR (0.53) | TTRKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL11865489 | 0.92 | LTB4R (0.52) | TTRKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL11858285 | 0.92 | TTR (0.56) | TTRKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL11861397 | 0.90 | NPC1 (0.44) | TTRKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL11866838 | 0.86 | KDM4E (0.58) | TTRKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL11859214 | 0.85 | TTR (0.60) | TTRKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL11367593 | 0.84 | TTR (0.59) | TTRKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL11872913 | 0.84 | TTR (0.59) | TTRKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL11872123 | 0.84 | TTR (0.59) | TTRKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL11858573 | 0.84 | TTR (0.59) | TTRKDM4EMEN1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3949084-A | Novel substituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-04-06 | — | — | US | disclosed |