Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 6/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR1D | P28221 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11858984 | 0.90 | TTR (0.55) | NPC1RAB9AKDM4EMEN1ALDH1A1 | |
| SCHEMBL11866688 | 0.83 | TTR (0.53) | NPC1RAB9AKDM4EMEN1ALDH1A1 | |
| SCHEMBL11770648 | 0.83 | NPC1 (0.39) | NPC1RAB9AKDM4EMEN1ALDH1A1 | |
| SCHEMBL11865489 | 0.82 | LTB4R (0.52) | NPC1RAB9AKDM4EMEN1ALDH1A1 | |
| SCHEMBL11858285 | 0.81 | TTR (0.56) | NPC1RAB9AKDM4EMEN1ALDH1A1 | |
| SCHEMBL11767062 | 0.81 | NPC1 (0.37) | NPC1RAB9AKDM4EMEN1ALDH1A1 | |
| SCHEMBL11337294 | 0.80 | TTR (0.60) | NPC1RAB9AKDM4EMEN1ALDH1A1 | |
| SCHEMBL11866838 | 0.76 | KDM4E (0.58) | NPC1RAB9AKDM4EMEN1ALDH1A1 | |
| SCHEMBL11859214 | 0.75 | TTR (0.60) | NPC1RAB9AKDM4EMEN1ALDH1A1 | |
| SCHEMBL11863181 | 0.75 | ALDH1A1 (0.43) | NPC1RAB9AKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3949084-A | Novel substituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-04-06 | — | — | US | disclosed |