SCHEMBL11859367

SCHEMBL11859367

CC(C)CNc1cccc(Br)[n+]1[O-]

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.33
IDH1 O75874 1/20 0.32
GAA P10253 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
ESR1 P03372 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11861034 0.79 ESR1 (0.36) IDO1IDH1GAAKMT2AHSD17B10
SCHEMBL11863929 0.77 L3MBTL1 (0.33) IDO1
SCHEMBL11865337 0.77 TDP1 (0.34) HSD17B10
SCHEMBL11860764 0.73 CYP1A2 (0.38) KMT2A
SCHEMBL11864993 0.63 CYP1A2 (0.35)
SCHEMBL943724 0.62
SCHEMBL5865099 0.62 GABRA1 (0.38)
SCHEMBL1419584 0.62 GAA (0.46) IDO1GAAKMT2A
SCHEMBL16833996 0.61 ESR1 (0.47) IDH1ESR1
SCHEMBL28607126 0.61 IDO1 (0.49) IDO1KMT2AESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3948910-A Aminohalopyridine-N-oxides THE DOW CHEMICAL COMPANY (US) 1976-04-06 US claimed
US-3948910-A Aminohalopyridine-N-oxides THE DOW CHEMICAL COMPANY (US) 1976-04-06 US disclosed