Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11890779 | 0.82 | NAALAD2 (0.45) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL12587323 | 0.82 | NAALAD2 (0.45) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL24245837 | 0.75 | ALDH1A1 (0.45) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL120318 | 0.73 | — | — | |
| SCHEMBL11529406 | 0.73 | NAALAD2 (0.50) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL15100349 | 0.73 | NAALAD2 (0.50) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL29293790 | 0.72 | LMNA (0.33) | ALDH1A1LMNAALKBH5SUCNR1EGLN1 | |
| SCHEMBL19418849 | 0.72 | NAALAD2 (0.37) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| SCHEMBL12221870 | 0.71 | ALDH1A1 (0.47) | NAALAD2ALDH1A1MEN1CYP1A2THRB | |
| Ammonia Solution, Strong SCHEMBL8995890 | 0.70 | NAALAD2 (0.48) | NAALAD2ALDH1A1MEN1CYP1A2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3979547-A | POLYURETHANES | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1976-09-07 | — | — | US | disclosed |