Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.70 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.70 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | TTR | P02766 | 9/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.44 |
| ▸ | ACSL6 | Q9UKU0 | 2/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11868704 | 0.90 | KDM4E (0.61) | ALDH1A1KDM4EHPGDMEN1TP53 | |
| SCHEMBL11865533 | 0.88 | KDM4E (0.58) | ALDH1A1KDM4EHPGDMEN1TP53 | |
| SCHEMBL11868372 | 0.86 | KDM4E (0.59) | ALDH1A1KDM4EHPGDMEN1TP53 | |
| SCHEMBL9151805 | 0.84 | ALDH1A1 (0.77) | ALDH1A1KDM4EHPGDMEN1TP53 | |
| SCHEMBL11322640 | 0.83 | TTR (0.80) | ALDH1A1KDM4EHPGDMEN1TP53 | |
| SCHEMBL12930824 | 0.83 | TTR (0.61) | ALDH1A1KDM4EHPGDMEN1TP53 | |
| SCHEMBL29627447 | 0.82 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDMEN1TP53 | |
| SCHEMBL1163801 | 0.82 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDMEN1TP53 | |
| SCHEMBL11862647 | 0.81 | KMT2A (0.68) | ALDH1A1KDM4EHPGDMEN1TP53 | |
| SCHEMBL11860605 | 0.81 | KDM4E (0.72) | ALDH1A1KDM4EHPGDMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3949084-A | Novel substituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-04-06 | — | — | US | disclosed |