SCHEMBL29627447

SCHEMBL29627447

CC(C)Oc1ccc2c(=O)c3cc(C(=O)O)ccc3oc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 1.00
KMT2A Q03164 5/20 1.00
KDM4E B2RXH2 4/20 1.00
HPGD P15428 4/20 1.00
HSD17B10 Q99714 3/20 1.00
MEN1 O00255 3/20 1.00
TP53 P04637 2/20 1.00
CYP2C9 P11712 1/20 1.00
PTGER1 P34995 1/20 1.00
PTGER3 P43115 1/20 1.00
PTGER2 P43116 1/20 1.00
PTGDR Q13258 1/20 1.00
TTR P02766 7/20 0.60
LMNA P02545 3/20 0.51
GAA P10253 2/20 0.51
AKR1B1 P15121 1/20 0.51
MAPT P10636 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
CYP3A4 P08684 1/20 0.50
NPC1 O15118 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1163801 1.00 ALDH1A1 (1.00) ALDH1A1KMT2AKDM4EHPGDHSD17B10
SCHEMBL10453911 0.95 KDM4E (0.90) ALDH1A1KMT2AKDM4EHPGDHSD17B10
SCHEMBL10454177 0.94 KDM4E (0.88) ALDH1A1KMT2AKDM4EHPGDHSD17B10
SCHEMBL10454176 0.94 KDM4E (0.88) ALDH1A1KMT2AKDM4EHPGDHSD17B10
Xanoxic Acid SCHEMBL2109668 0.93 ALDH1A1 (0.88) ALDH1A1KMT2AKDM4EHPGDHSD17B10
SCHEMBL9151805 0.87 ALDH1A1 (0.77) ALDH1A1KMT2AKDM4EHPGDHSD17B10
SCHEMBL8961859 0.85 ALDH1A1 (0.72) ALDH1A1KMT2AKDM4EHPGDHSD17B10
SCHEMBL10453816 0.84 ALDH1A1 (0.72) ALDH1A1KMT2AKDM4EHPGDHSD17B10
SCHEMBL11860605 0.84 KDM4E (0.72) ALDH1A1KMT2AKDM4EHPGDHSD17B10
SCHEMBL11322640 0.83 TTR (0.80) ALDH1A1KMT2AKDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022128052-A1 MEDICAMENT FOR FIGHTING INFLAMMATORY CONDITIONS OF HUMAN SKIN SYMRISE AG (DE) 2022-06-23 WO disclosed