Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195043 | 0.86 | MAPT (0.67) | MAPTALDH1A1LMNATSHRTDP1 | |
| SCHEMBL11012447 | 0.83 | MAPT (0.60) | MAPTALDH1A1LMNATSHRTDP1 | |
| SCHEMBL5955457 | 0.83 | ALDH1A1 (0.60) | MAPTALDH1A1LMNATSHRTDP1 | |
| SCHEMBL5348283 | 0.83 | TDP1 (0.65) | MAPTALDH1A1LMNATSHRTDP1 | |
| SCHEMBL914291 | 0.82 | TDP1 (0.58) | MAPTALDH1A1LMNATSHRTDP1 | |
| SCHEMBL30060469 | 0.81 | MAPT (0.58) | MAPTALDH1A1LMNATSHRTDP1 | |
| SCHEMBL7807114 | 0.81 | MAPT (0.58) | MAPTALDH1A1LMNATSHRTDP1 | |
| SCHEMBL1373865 | 0.80 | HSPB1 (0.57) | MAPTALDH1A1LMNATSHRTDP1 | |
| SCHEMBL11655847 | 0.80 | MAPT (0.56) | MAPTALDH1A1LMNATSHRTDP1 | |
| SCHEMBL11015121 | 0.80 | MAPT (0.56) | MAPTALDH1A1LMNATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3965113-A | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity | SYNTEX (U.S.A.) INC. (US) | 1976-06-22 | — | — | US | disclosed |