Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11863260 | 0.86 | RIPK1 (0.38) | TP53 | |
| SCHEMBL11877163 | 0.84 | HCRTR2 (0.40) | HCRTR2KMT2APABPC1RAB9AHTR1A | |
| SCHEMBL11862536 | 0.82 | HCRTR2 (0.44) | HCRTR2 | |
| SCHEMBL11865367 | 0.81 | HCRTR1 (0.43) | HCRTR2TP53HTR1A | |
| SCHEMBL11868723 | 0.80 | CYP1A2 (0.45) | HCRTR2TP53PARP1PABPC1CYP3A4 | |
| SCHEMBL11867419 | 0.80 | CHRNB4 (0.38) | MEN1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11863635 | 0.80 | HTR2B (0.43) | PTGS1HTR1A | |
| SCHEMBL11870882 | 0.79 | SSTR4 (0.38) | HCRTR2CYP3A4 | |
| SCHEMBL11863586 | 0.79 | HCRTR2 (0.37) | HCRTR2TP53PARP1PABPC1CYP3A4 | |
| SCHEMBL11869983 | 0.69 | TDP1 (0.46) | MEN1KMT2ACYP3A4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3976663-A | INSECTICIDE | THE PROCTER & GAMBLE COMPANY (US) | 1976-08-24 | — | — | US | disclosed |