Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11877163 | 0.85 | HCRTR2 (0.40) | HCRTR2HTR2BSIGMAR1HTR1ACYP19A1 | |
| SCHEMBL11862536 | 0.84 | HCRTR2 (0.44) | HCRTR1HCRTR2DRD2DRD3 | |
| SCHEMBL11864992 | 0.81 | HCRTR2 (0.43) | HCRTR2HTR1ATP53 | |
| SCHEMBL11866412 | 0.81 | CYP1A2 (0.44) | HCRTR1HCRTR2HTR2BSIGMAR1HTR1A | |
| SCHEMBL11866419 | 0.81 | CYP1A2 (0.44) | HCRTR1HCRTR2HTR2BSIGMAR1HTR1A | |
| SCHEMBL11867419 | 0.81 | CHRNB4 (0.38) | LMNA | |
| SCHEMBL11863635 | 0.81 | HTR2B (0.43) | HTR2BSIGMAR1HTR1AHTR7TMEM97 | |
| SCHEMBL11870882 | 0.80 | SSTR4 (0.38) | HCRTR2HTR2BCYP19A1 | |
| SCHEMBL11869529 | 0.78 | HCRTR1 (0.37) | HCRTR1HCRTR2HTR2BSIGMAR1HTR1A | |
| SCHEMBL11863260 | 0.78 | RIPK1 (0.38) | TP53LMNADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3976663-A | INSECTICIDE | THE PROCTER & GAMBLE COMPANY (US) | 1976-08-24 | — | — | US | claimed |
| US-3976663-A | INSECTICIDE | THE PROCTER & GAMBLE COMPANY (US) | 1976-08-24 | — | — | US | disclosed |