SCHEMBL11865035

SCHEMBL11865035

CC(Oc1cccc2ccccc12)C(=O)NN

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.64
GAA P10253 3/20 0.64
OGG1 O15527 2/20 0.52
PGR P06401 1/20 0.49
PTGS1 P23219 1/20 0.49
MAPK1 P28482 1/20 0.49
HSD17B10 Q99714 1/20 0.49
CARM1 Q86X55 1/20 0.47
PRMT6 Q96LA8 1/20 0.47
MAPT P10636 1/20 0.47
CASP1 P29466 1/20 0.46
CASP3 P42574 1/20 0.46
CASP7 P55210 1/20 0.46
CASP6 P55212 1/20 0.46
CASP8 Q14790 1/20 0.46
TSHR P16473 1/20 0.45
PPARG P37231 2/20 0.45
PPARA Q07869 2/20 0.45
PSMB5 P28074 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10722783 0.86 ALDH1A1 (0.50) ALDH1A1GAAPGRPTGS1MAPK1
SCHEMBL31376353 0.83 ALDH1A1 (0.49) ALDH1A1GAAOGG1PGRPTGS1
SCHEMBL5941038 0.83 ALDH1A1 (0.49) ALDH1A1GAAOGG1PGRPTGS1
SCHEMBL11259835 0.82 TSHR (0.56) ALDH1A1MAPTTSHR
SCHEMBL10631675 0.82 TSHR (0.56) ALDH1A1MAPTTSHR
SCHEMBL23691076 0.82 SMN1; SMN2 (0.52) ALDH1A1GAAPGRPTGS1MAPK1
Benzene SCHEMBL27947280 0.81 PPARG (0.50) ALDH1A1GAAOGG1PGRPTGS1
SCHEMBL11866215 0.81 OGG1 (0.52) ALDH1A1GAAOGG1PGRPTGS1
SCHEMBL2922977 0.81 PPARG (0.64) ALDH1A1GAAPGRPTGS1MAPK1
SCHEMBL16933413 0.81 PPARG (0.64) ALDH1A1GAAPGRPTGS1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3972905-A FUNGICIDE BAYER AKTIENGESELLSCHAFT (DT) 1976-08-03 US disclosed