Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | TNKS | O95271 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7623510 | 0.76 | MAPT (0.65) | KDM4EKMT2ATNKSMAPTMEN1 | |
| SCHEMBL11863327 | 0.76 | KDM4E (0.57) | KDM4EKMT2ATNKSMAPTMEN1 | |
| SCHEMBL7623370 | 0.76 | CUL4A (0.67) | KDM4EKMT2ATNKSMAPTMEN1 | |
| SCHEMBL11870722 | 0.76 | KDM4E (0.64) | KDM4EKMT2ATNKSMAPTMEN1 | |
| SCHEMBL11868950 | 0.75 | KDM4E (0.54) | KDM4EKMT2ATNKSMAPTMEN1 | |
| SCHEMBL11868321 | 0.72 | TNKS (0.69) | KDM4EKMT2ATNKSMAPTMEN1 | |
| SCHEMBL11326239 | 0.71 | KMT2A (0.53) | KDM4EKMT2ATNKSMAPTMEN1 | |
| SCHEMBL7621183 | 0.70 | KDM4E (0.55) | KDM4EKMT2ATNKSMAPTMEN1 | |
| SCHEMBL11869542 | 0.70 | TNKS (0.52) | KDM4EKMT2ATNKSMAPTMEN1 | |
| SCHEMBL11868728 | 0.69 | ALOX15 (0.62) | KDM4EKMT2ATNKSMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3987196-A | FUNGISTATS | ELI LILLY AND COMPANY (US) | 1976-10-19 | — | — | US | disclosed |