Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 13/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11866232 | 1.00 | TGM2 (0.44) | TGM2RENKMT2AL3MBTL1MAPK8 | |
| SCHEMBL30179356 | 0.84 | KMT2A (0.51) | TGM2RENKMT2AL3MBTL1 | |
| SCHEMBL30051243 | 0.84 | KMT2A (0.51) | TGM2RENKMT2AL3MBTL1 | |
| SCHEMBL30179468 | 0.84 | KMT2A (0.51) | TGM2RENKMT2AL3MBTL1 | |
| SCHEMBL30412022 | 0.83 | TGM2 (0.46) | TGM2RENMAPK8MAPK9MAPK10 | |
| SCHEMBL38658073 | 0.81 | CALCRL (0.45) | TGM2RENMAPK8MAPK9MAPK10 | |
| SCHEMBL30716931 | 0.80 | NTSR1 (0.55) | — | |
| SCHEMBL11857309 | 0.80 | NTSR2 (0.46) | — | |
| SCHEMBL11857288 | 0.80 | NTSR2 (0.46) | — | |
| SCHEMBL30844257 | 0.80 | PRMT5 (0.42) | RENMAPK8MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3947575-A | Peptides as argiotensin converting enzyme inhibitors | E. R. SQUIBB & SONS, INC. (US) | 1976-03-30 | — | — | US | disclosed |